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Case Challenge: Clinical Encounters In Mood Disorders and Maintenance Therapy in Bipolar Disorder

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neuroscienceCME Medical Simulation

Premiere Date: Friday, February 3, 2012

This activity offers CE credit for:

  1. Physicians (CME)
  2. Nurses (CNE)
  3. Social Workers (NASW)
  4. Certified Case Managers (CCMC)
  5. Pharmacists (ACPE)


All other clinicians will receive a Certificate of Attendance stating this activity was certified for AMA PRA Category 1 Creditâ„¢

Credit Expiration Date:
Sunday, February 3, 2013
Note: Credit Is No Longer Available

Faculty


Paul E. Keck, Jr., MDPaul E. Keck, Jr., MD 
President-CEO, Lindner Center of HOPE
Professor of Psychiatry & Behavior Neuroscience
University of Cincinnati College of Medicine
Cincinnati, OH

Statement of Need

Psychiatrists and generalist clinicians frequently encounter patients with mood disorders, including bipolar disorder (BPD); however, many of these patients do not receive optimal care. When their illness is untreated or undertreated, these patients often experience poor outcomes such as global impairment, emergence of comorbid conditions, increased hospitalizations, and increased risk of suicide. Clinicians need to be able to assimilate information from evidence-based clinical guidelines and trials (e.g., STEP-BD, STAR*D) to improve care delivery to patients with BPD. Specifically, prompt intervention for the acute mania episode is imperative, with careful consideration given to often-present comorbidities. Once the acute episode is stabilized, maintenance treatment, pharmacotherapy, patient and family education, and psychosocial support must be considered to prevent relapse and improve functioning.

This neuroscienceCME Medical Simulation puts the clinician the lifelong learner in the drivers seat as the decision-maker who is providing care for a patient across two or three clinical encounters. As such, clinicians have the opportunity to put their knowledge into practice with this virtual patient, and then translate their experience to their practice with actual patients with bipolar disorder.


  • Grunze H, Kasper S, Goodwin G, et al. The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders, Part II: Treatment of Mania. World J Biol Psychiatry. 2003;4(1):5-13. PMID: 12582971.
  • Nierenberg AA. What have we learned about bipolar disorder from STEP-BD and other practical trials? J Clin Psychiatry. 2009;70(8):e30. PMID: 19758519.

Activity Goal

To meet specified learning objectives regarding bipolar disorder so that clinician knowledge and competence are increased, and more clinicians 1) address nonadherence; 2) diagnose and manage comorbid conditions; and 3) use systematic trials to devise individualized therapy regimens for patients with bipolar disorder.

Learning Objectives

At the end of this CE activity, participants should be able to:

  • Implement best practices for assessing and addressing treatment adherence in patients with bipolar disorder.
  • Diagnose and manage neuropsychiatric conditions that are commonly comorbid with bipolar disorder and that require treatment to improve patient outcomes.
  • Perform systematic drug trials in order to devise the optimal individualized therapy regimen for each patient with bipolar disorder.

Financial Support

The Indiana University School of Medicine and CME Outfitters, LLC gratefully acknowledge an educational grant from Bristol-Myers Squibb Company and Otsuka America Pharmaceutical, Inc., in support of this CE activity.

Target Audience

Physicians, physician assistants, nurses, nurse practitioners, pharmacists, and other health care professionals interested in mental health.

Credit Information

CME Credit (Physicians):
CME Accreditation (Physicians): Indiana University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Indiana University Medical School designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Creditâ„¢. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Note: While it offers CME credits, this activity is not intended to provide extensive training or certification in the field.

CNE Credit (Nurses):
Provider approved by the California Board of Registered Nursing, Provider Number CEP 15510, for 1.0 contact hours.

NASW Credit (Social Workers):
This program was approved by the National Association of Social Workers (provider #886407722) for 1 continuing education contact hour.

CCMC Credit (Certified Case Managers):
This program has been approved for 1 hour by the Commission for Case Manager Certification (CCMC).

CPE Credit (Pharmacists):
ACPE CME Outfitters, LLC, is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. 1.0 contact hours (0.1 CEUs) Universal Activity Number: 0376-0000-12-005-H01-P
Activity Type: application-based

Post-tests, credit request forms, and activity evaluations must be completed online at www.cmeoutfitters.com/test (requires free account activation), and participants can print their certificate or statement of credit immediately (80% pass rate required). This website supports all browsers except Internet Explorer for Mac. For complete technical requirements and privacy policy, visit www.neurosciencecme.com/technical.asp.

Disclosure Declaration

In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support, educational programs sponsored by Indiana University School of Medicine (IUSM) must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, and planning committee members participating in an IUSM-sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services that are discussed in an educational activity. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Keck has disclosed that he has served as a consultant to Sepracor, Inc., Bristol-Myers Squibb Company, GlaxoSmithKline, Pfizer Inc., QuantiaMD, and Schering-Plough Corporation. Dr. Keck is a co-inventor on the United States Patent No. 6,387,956: Shapira NA, Goldsmith TD, Keck, PE Jr. (University of Cincinnati) Methods of treating obsessive-compulsive spectrum disorder comprises the step of administering an effective amount of tramadol to an individual. Filed March 25, 1999; approved May 14, 2002. Dr. Keck has received no financial gain from this patent.

CME Reviewer:Amit Anand, MD discloses that over the past 2 years he has been a consultant for Dey Pharmaceuticals and Pfizer and have had grant funding from Astra-Zeneca and Lilly.

For IU CME Staff: Hassan Danesh, PhD and Monica Armin have disclosed that they have no potential or actual conflicts of interest.

Monique Johnson, MD, CCMEP (planning committee) has no disclosures to report.

Joy B. Leffler, MLA, NASW, CSE (planning committee) has no disclosures to report.

Sharon Tordoff, CCMEP (planning committee) has no disclosures to report.

Unlabeled Use Disclosure

Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

Indiana University School of Medicine, CME Outfitters, LLC, the faculty, Bristol-Myers Squibb Company and Otsuka America Pharmaceutical, Inc. do not endorse the use of any product outside of the FDA labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use.

Questions about this activity? Call us at 877.CME.PROS (877.263.7767).

PL-036-020312-08

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