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Atypicals in Practice: Case Studies on Switching

neuroscienceCME TV

Premiere Date: Wednesday, November 7, 2007

This activity offers CE credit for:

1. Physicians (ACCME/AMA PRA Category 1)
2. Nurses (CNE)
3. Pharmacists (ACPE)
4. Psychologists (APA)
5. Social Workers (NASW)
6. Certified Case Managers (CCMC)

All other clinicians will receive a Certificate of Attendance stating this activity was certified for AMA PRA Category 1 Credit™

Credit Expiration Date:
Friday, November 7, 2008
Note: Credit Is No Longer Available

Faculty

Alexander L. Miller, MD  Hugo A. Auler Professor in Psychiatry University of Texas Health Science Center at San Antonio San Antonio, TX

John W. Newcomer, MD  Senior Associate Dean for Clinical Research Leonard M. Miller Professor of Psychiatry and Behavioral Sciences Leonard M. Miller School of Medicine University of Miami Miami, FL

Statement of Need

Most clinicians initiate antipsychotic therapy for their patients from a perspective that integrates scientific evidence with experience. But many times, a lack of treatment response or treatment emergent side effects warrant a switch to a different agent. In the CATIE trial, 74% of the 1432 patients discontinued their medication within 18 month of initiation.(1) Side effects such as EPS, sedation, galactorrhea, amenorrhea, weight gain, and dyslipidemia may not only affect quality of life, but may also put the patient at increased risk for medical disorders including cardiovascular disease. The process of switching is difficult and carries with it an element of risk. Switching requires planning, appropriate dosing that considers receptor binding, and the active involvement of the patient and caregivers. In this evidence-based neuroscienceCME TV activity, the experts will use a case-based format to explore the complexities of switching patients to a new antipsychotic when side effects and symptom control impact quality of life and patient outcomes.

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1. Lieberman JA, et al. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med 2005;353:1209-1223.

Activity Goal

To utilize appropriate switching techniques for patients who do not achieve the optimal therapeutic response or have treatment emergent side effects.

Learning Objectives

At the end of this CE activity, participants should be able to:

• Describe factors that lead to discontinuation of atypical antipsychotics.
• Identify treatment-emergent side effects that may necessitate a strategy for switching antipsychotic therapy.
• Employ techniques for switching antipsychotics that minimize risk and improve patient outcomes.

Target Audience

Physicians, physician assistants, nurse practitioners, nurses, psychologists, social workers, certified case managers, pharmacists, and other healthcare professionals with an interest in mental health.

Credit Information

CME Credit (Physicians):
CME Outfitters, LLC, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. CME Outfitters, LLC, designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

CNE Credit (Nurses):
CME Outfitters, LLC, is an approved provider of continuing nursing education by the New York State Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation.

It has been assigned code 6WASUP-PRV-0618. 1.0 contact hours will be awarded upon successful completion.
Note to Nurse Practitioners: The content of this CNE activity pertains to Pharmacology.

CEP Credit (Psychologists):
CME Outfitters is approved by the American Psychological Association to sponsor continuing education for psychologists. CME Outfitters maintains responsibility for this program and its content. (1.0 CE credits)

NASW Credit (Social Workers):
This program was approved by the National Association of Social Workers (provider #886407722) for 1 continuing education contact hour.

CCMC Credit (Certified Case Managers):
This program has been approved for 1 hour by the Commission for Case Manager Certification (CCMC).

CPE Credit (Pharmacists):
CME Outfitters, LLC, is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. 1.0 contact hours (0.1 CEUs)
Universal Program Number: 376-999-07-020-L01 (live presentation) 376-999-07-020-H01 (recorded programs)

Post-tests, credit request forms, and activity evaluations can be completed online at www.neuroscienceCME.com (click on the Testing/Certification link under the Resources tab - requires free account activation), and participants can print their certificate or statement of credit immediately (70% pass rate required). Otherwise, participants should fully complete and return both the credit request form and activity evaluation located within the course guide for this activity. A certificate or statement of credit will be mailed within 4-6 weeks to all who successfully complete these requirements.

Disclosure Declaration

All faculty participating in CME Outfitters continuing education activities are required to disclose any conflict(s) of interest related to the content of their presentation(s) as defined by the ACCME's Standards for Commercial Support, and other accrediting and regulatory bodies. Full disclosure of faculty relationships will be made on this website and within the activity course materials prior to the premiere date of this activity.

Questions about this activity? Call us at 877.CME.PROS (877.263.7767).